- Formula
- C187H291N45O59
- Molecular weight
- 4114 g/mol
- CAS
- 910463-68-2
- PubChem CID
- 56843331 ↗

Vita SM5 10mg
Semaglutide · Lyophilized powder (vial)
Add $120 more for free Xpresspost.
- Delivery guaranteeLost or seized: reshipped free
- Tracking in 72 hPacked in Vancouver
- Interace-TransferFrom any Canadian bank
- Plain packagingNo product names outside
Overview
SM5 is the store’s name for semaglutide, a long-acting GLP-1 receptor agonist. In Canada it is a prescription medicine for type 2 diabetes and for weight management.
How it works
It mimics the gut hormone GLP-1: it slows stomach emptying, increases insulin release when blood sugar is high and acts on appetite centres in the brain. A fatty side chain lets it bind albumin, which stretches its half-life to about a week.
Chemistry
From PubChem, the US National Library of Medicine’s chemistry database.
Clinical reference
Health Canada’s weight-management labelling starts at 0.25 mg once a week for four weeks, then steps up every four weeks (0.5, 1, 1.7 mg) to a maintenance amount of 2.4 mg a week. Diabetes labelling stops at 2 mg a week.
Label and guideline amounts are shown for reference only. They are not a recommendation, and we never give cycle or performance amounts. Any use belongs under a doctor’s care, with bloodwork.
Measuring calculator
Converts an amount you enter into what to measure. It does not suggest an amount.
Strength used: 10 mg per vial
Injection sites
SM5 10mg is a freeze-dried powder. After mixing with bacteriostatic water, compounds like this are usually injected subcutaneously (subQ): into the fat just under the skin with a short insulin needle.
- Volume per site
- About 1 ml or less
- Needle
- 4 to 13 mm insulin needle, 29 to 31G
Finding it. Anywhere on the belly at least 5 cm from the navel, avoiding scars and the belt line. Pinch a fold of skin and inject into it.
Why it is used. The most-used subcutaneous site: easy to see, plenty of fat and steady absorption. Weekly GLP-1 pens list it first.
Watch out. Move each injection 2 to 3 cm from the last to avoid hard lumps.
- Volume per site
- About 1 ml or less
- Needle
- 4 to 13 mm insulin needle, 29 to 31G
Finding it. The middle of the front of the thigh, a hand-width below the hip and a hand-width above the knee.
Why it is used. Easy to reach seated and a good second site to rotate with the belly.
Watch out. Absorption can be a little slower than the belly.
- Volume per site
- About 1 ml or less
- Needle
- 4 to 13 mm insulin needle, 29 to 31G
Finding it. The fleshy back of the upper arm, halfway between shoulder and elbow.
Why it is used. A third site to rotate through so each spot rests longer.
Watch out. Hard to pinch and reach on yourself; a helper makes it easier.
Why these sites for SM5 10mg
Subcutaneous (subQ)- Belly first. The abdomen has the most fat and the steadiest absorption, and you can see what you are doing.
- Short needle, small volume. About 1 ml or less per spot with an insulin syringe. Pinch the skin if you are lean.
- Move every time. Keep each injection 2 to 3 cm from the last to avoid lumps.
Every time: wash your hands, wipe the vial stopper and skin with alcohol, use a new sterile needle and syringe, and never share. See a doctor for spreading redness, heat, swelling, pus, fever or numbness. This is general guidance from standard nursing practice, not medical advice; a pharmacist or nurse can show you in person.
Combinations and interactions
Prescribed or used alongside
- Bacteriostatic water to mix the powder and U-100 insulin syringes to measure it.
- In practice it is prescribed alongside diet and activity changes, not combined with other GLP-1 class drugs.
Drug interactions
- Insulin and sulfonylureas: higher risk of low blood sugar.
- Oral medicines: slower stomach emptying can change how fast pills are absorbed.
Risks and bloodwork
The most common effects, mostly when the amount is increased.
Rare; severe stomach pain that spreads to the back needs urgent care.
Rapid weight loss increases gallstone risk.
Not used by people with a personal or family history of medullary thyroid cancer.
Bloodwork doctors check
- Fasting glucose and HbA1c
- Kidney function (creatinine, eGFR)
- Lipase if stomach pain appears
- Resting heart rate
- Weight and waist measurements
Not for
People under 18, anyone pregnant or breastfeeding, anyone with active cancer or a history of cancer, and anyone with diabetes unless a doctor is involved.
Canadian legal status
In Canada this is a prescription drug under the Food and Drugs Act. Using it under a doctor’s care, with bloodwork, is how it is meant to be used. This is general information, not legal advice.
References
- Once-Weekly Semaglutide in Adults with Overweight or ObesityWilding JPH et al. · N Engl J Med, 2021 · PMID 33567185
- Safety of SemaglutideSmits MM, Van Raalte DH · Front Endocrinol (Lausanne), 2021 · PMID 34305810
- Acute pancreatitis due to different semaglutide regimens: An updated meta-analysisMasson W et al. · Endocrinol Diabetes Nutr (Engl Ed), 2024 · PMID 38555109
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FAQ
Why is it called SM5?
SM5 is the store’s product name for this GLP-1 research peptide.
How long does it last?
About seven days, which is why the clinical schedule is weekly.
What do I need with it?
Bacteriostatic water and U-100 insulin syringes.
How fast will it arrive?
Orders ship from Vancouver by Canada Post Xpresspost. You get a tracking number within 72 hours of payment; delivery then takes 1 to 2 business days in BC, 3 to 4 in Ontario and 3 to 5 in Quebec.
What if my parcel is lost or seized?
We reship it free. Contact us with your order number.
Adults 18+. This page is general information, not medical advice. Talk to a licensed healthcare provider before using any compound.






