2D structure · PubChem CID 110635Tadalafil

ZionovaSexual healthSKU ZionovaCialis

Zionova Cialis

Tadalafil · Oral tablet

4.9 from 68 reviews

$132CAD

In stock, ships from Vancouver

Strength50 mg per tablet

Pack50 tablets

Total per order2,500 mg

Half-life≈ 17.5 hours

Add $168 more for free Xpresspost.

Delivery guaranteeLost or seized: reshipped free
Tracking in 72 hPacked in Vancouver
Interace-TransferFrom any Canadian bank
Plain packagingNo product names outside

Overview

Cialis is tadalafil, a PDE5 inhibitor for erectile dysfunction and enlarged prostate. It lasts far longer than sildenafil.

How it works

It blocks PDE5, which lets cGMP build up in penile blood vessels after sexual stimulation, improving blood flow. It does not cause an erection without stimulation.

Chemistry

From PubChem, the US National Library of Medicine’s chemistry database.

Tadalafil

Formula: C₂₂H₁₉N₃O₄
Molecular weight: 389.4 g/mol
CAS: 171596-29-5
PubChem CID: 110635 ↗

Clinical reference

The label amount is 10 mg before sex (5 to 20 mg range), no more than once a day, or 2.5 to 5 mg once daily. 20 mg a day is the maximum.

Label and guideline amounts are shown for reference only. They are not a recommendation, and we never give cycle or performance amounts. Any use belongs under a doctor’s care, with bloodwork.

Measuring calculator

Converts an amount you enter into what to measure. It does not suggest an amount.

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Strength used: 50 mg per tablet · pack: 50 tablets

Combinations and interactions

Prescribed or used alongside

Not combined with other PDE5 inhibitors except under a doctor’s direction.

Drug interactions

Nitrates (nitroglycerin, isosorbide) and poppers: dangerous drop in blood pressure; never combine.
Alpha blockers: can lower blood pressure further.
Strong CYP3A4 inhibitors (ketoconazole, ritonavir, grapefruit): raise tadalafil levels.

Risks and bloodwork

Strength above the label

Some tablets here contain more than the 20 mg maximum; check the strength line.

Headache and back pain

Common, especially back pain with tadalafil.

Priapism

An erection lasting over four hours is an emergency.

Vision or hearing loss

Sudden loss needs urgent care.

Bloodwork doctors check

Blood pressure
A heart check if you have heart disease or chest pain

Not for

People under 18, anyone pregnant or breastfeeding, and anyone with liver disease, heart disease, uncontrolled blood pressure or a hormone-sensitive cancer, unless a doctor directs otherwise.

Canadian legal status

In Canada this is a prescription drug under the Food and Drugs Act. Using it under a doctor’s care, with bloodwork, is how it is meant to be used. This is general information, not legal advice.

References

Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysisGong B et al. · Int Urol Nephrol, 2017 · PMID 28741090
Phosphodiesterase Type 5 Inhibitors and Oral Nitrates in Male Patients with Ischemic Heart DiseaseMorrisette MJ, Dunn SP · Curr Cardiol Rep, 2023 · PMID 37074567

Reviews

4.968 reviews from customers

Reviews are published after a quick check. Only customers who bought this product can review it.

Brian B.Verified buyerSep 28, 2025

Perfect