2D structure · PubChem CID 178024Ibutamoren (MK-677)

ZionovaWeight lossSKU ZIO-MK677

Zionova MK 677

Ibutamoren (MK-677) · Oral tablet

5.0 from 5 reviews

$132CAD

In stock, ships from Vancouver

Strength10 mg per tablet

Pack50 tablets

Total per order500 mg

Half-life≈ 24 hours

Add $168 more for free Xpresspost.

BUY 3+ SAVE 5% · 5+ SAVE 10%

Complete your cycle

What most customers add with this:

Zionova Clomid$114.00 · Recovery after your cycle

Add

Delivery guaranteeLost or seized: reshipped free
Tracking in 72 hPacked in Vancouver
Interace-TransferFrom any Canadian bank
Plain packagingNo product names outside

Overview

MK-677 (ibutamoren) is an oral growth-hormone secretagogue. It is often grouped with SARMs but works in a different way.

How it works

It mimics ghrelin, raising growth hormone and IGF-1 for about a day per dose, and increases appetite.

Chemistry

From PubChem, the US National Library of Medicine’s chemistry database.

Ibutamoren (MK-677)

Formula: C₂₇H₃₆N₄O₅S
Molecular weight: 528.7 g/mol
CAS: 159634-47-6
PubChem CID: 178024 ↗

Clinical reference

Clinical trials in older adults used 10 to 25 mg once a day, for up to two years. It is not approved for any use.

Label and guideline amounts are shown for reference only. They are not a recommendation, and we never give cycle or performance amounts. Any use belongs under a doctor’s care, with bloodwork.

Measuring calculator

Converts an amount you enter into what to measure. It does not suggest an amount.

Your amountEnter an amount to see the conversion.

Strength used: 10 mg per tablet · pack: 50 tablets

Combinations and interactions

Prescribed or used alongside

Not suppressive of testosterone, so it is not a SARM in the strict sense.

Drug interactions

Diabetes medicines: blood sugar rises.

Risks and bloodwork

Blood sugar

Insulin sensitivity falls; a trial was stopped early over heart failure concerns in frail patients.

Hunger

Strong appetite increase.

Water retention

Swelling and joint pain.

Sleep

Vivid dreams and changed sleep.

Bloodwork doctors check

IGF-1
Fasting glucose and HbA1c
Thyroid function (TSH, free T4)
Blood pressure

Not for

People under 18, anyone pregnant or breastfeeding, and anyone with liver disease, heart disease, uncontrolled blood pressure or a hormone-sensitive cancer, unless a doctor directs otherwise.

Canadian legal status

SARMs and related research compounds are not approved by Health Canada for human use, and Health Canada has warned consumers about products containing them. They are sold for research purposes and are banned in sport. This is general information, not legal advice.

References

Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjectsChapman IM et al. · J Clin Endocrinol Metab, 1996 · PMID 8954023
The effects of MK-0677, an oral growth hormone secretagogue, in patients with hip fractureBach MA et al. · J Am Geriatr Soc, 2004 · PMID 15066065
Prolonged oral treatment with MK-677, a novel growth hormone secretagogue, improves sleep quality in manCopinschi G et al. · Neuroendocrinology, 1997 · PMID 9349662

Reviews

5.05 reviews from customers

Reviews are published after a quick check. Only customers who bought this product can review it.

Brian B.Verified buyerAug 5, 2025

Hungry