Aromatization Inhibitors to Deal With Negative Side Effects From Steroid Use Aromatase inhibitors (AIs) drugs are synthetic nonaromatizable androgens that work by binding to the aromatase enzyme and inhibiting its activity. This results in decreased estrogen levels by preventing the aromatization of androgens into estrogens.

The most common AIs used in the treatment of gynecomastia are as follows:

1. Tamoxifen

2. Anastrozole

3. Letrozole

4. Exemestane

5. Arimidex